runt disease - meaning and definition. What is runt disease
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What (who) is runt disease - definition

MEDICAL CONDITION
GVHD; Graft versus host disease; Runt disease; Graft vs host disease; Graft v. host; Graft versus host; Graft-vs-host disease; Graft vs host; AGVHD; Graft Versus Host Disease; Graft vs. host disease; Graft-versus-Host Reaction; Graft vs. Host; Graft-versus-host; Graft-versus-host reaction; Graft-vs.-host disease; Graft vs. host syndrome; Billingham Criteria; Billingham criteria; GvHD; Graft vs host reaction
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  • GvHD pathology

Graft-versus-host disease         
Graft-versus-host disease (GvHD) is a syndrome, characterized by inflammation in different organs. GvHD is commonly associated with bone marrow transplants and stem cell transplants.
runt         
SMALLEST ANIMAL OF THE LITTER
Runt (litter); Runt of the litter
(runts)
The runt of a group of animals born to the same mother at the same time is the smallest and weakest of them.
Animals reject the runt of the litter.
N-COUNT: oft N of n
Runt         
SMALLEST ANIMAL OF THE LITTER
Runt (litter); Runt of the litter
·adj The dead stump of a tree; also, the stem of a plant.
II. Runt ·adj A variety of domestic pigeon, related to the barb and carrier.
III. Runt ·adj A dwarf; also, a mean, despicable, boorish person;
- used opprobriously.
IV. Runt ·adj Any animal which is unusually small, as compared with others of its kind;
- applied particularly to domestic animals.

Wikipedia

Graft-versus-host disease

Graft-versus-host disease (GvHD) is a syndrome, characterized by inflammation in different organs. GvHD is commonly associated with bone marrow transplants and stem cell transplants.

White blood cells of the donor's immune system which remain within the donated tissue (the graft) recognize the recipient (the host) as foreign (non-self). The white blood cells present within the transplanted tissue then attack the recipient's body's cells, which leads to GvHD. This should not be confused with a transplant rejection, which occurs when the immune system of the transplant recipient rejects the transplanted tissue; GvHD occurs when the donor's immune system's white blood cells reject the recipient. The underlying principle (alloimmunity) is the same, but the details and course may differ.

GvHD can also occur after a blood transfusion, known as Transfusion-associated graft-versus-host disease or TA-GvHD if the blood products used have not been gamma irradiated or treated with an approved leukocyte reduction system. In contrast to organ/tissue transplant associated GvHD, the incidence of TA-GvHD is increased with HLA matching (first-degree or close relatives).